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Our Lungs are constantly being challenged by environmental exposures (air pollutants, particulate matter, noxious gases, allergens, viruses, bacteria, etc). The central focus of our research is to explore and identify novel mechanisms of how environmental exposures can lead to lung and/or cardiovascular disease pathogenesis. We also have a great interest to understand how environmental exposures can alter the pulmonary immune response, making the lung more susceptible to infection. Of particular interest is determining the role of scavenger receptors in preventing infectious and inflammatory lung diseases. Our research, is currently funded by the Health Effects Institute (HEI), and we collaborate with multiple investigators at East Carolina University, Duke University, National Institutes of Environmental Health Sciences (NIEHS), University of North Carolina, and Vanderbilt University to collectively understand the health risks associated with environmental exposures. Our research provides fundamental information from basic and translational models of lung disease.