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Our lungs experience challenges daily from environmental exposures such as, air pollutants, particulate matter, noxious gases, allergens, viruses, and bacteria. The central focus of our lab is to identify and investigate novel mechanisms of environmental exposures and how they can lead to pulmonary pathogenesis. Specifically, we wish to elucidate the pathways in which environmental exposures alter the pulmonary immune response since this makes the lung more susceptible to infection. Lastly, our interests also lie in determining the role of scavenger receptors in preventing infectious and inflammatory lung diseases.
Our research, is currently funded by the National Institutes of Health, and we collaborate with multiple investigators at Ohio State University, Nationwide Children’s Hospital, Duke University, National Institutes of Environmental Health Sciences (NIEHS), University of North Carolina, and Vanderbilt University to collectively understand the health risks associated with environmental exposures.