Uncover molecular mechanisms by which air pollution increases susceptibility to pulmonary infections
Understand the influence of lipid mediators on the pulmonary inflammatory response following air pollution exposure
Evaluate how dietary fatty acids mitigate/influence environmental lung diseases
Determine if genetic diversity in specialized pro-resolving lipid mediator receptors influence the resolution of pulmonary inflammation following air pollution exposure
Assess alterations within the pulmonary microenvironment post ozone exposure that increase bacterial proliferation
Analyze transcriptional changes seen in mice exposed to ozone coupled with Klebisella pneumoniae infection
Understand the role of Macrophage Migration Inhibitory Factor during bacterial infection and/or ozone exposure within the pulmonary environment